Time course of pulmonary artery pressure during sleep in sleep apnoea syndrome : role of recurrent apnoeas
Identifieur interne : 00CA64 ( Main/Exploration ); précédent : 00CA63; suivant : 00CA65Time course of pulmonary artery pressure during sleep in sleep apnoea syndrome : role of recurrent apnoeas
Auteurs : E. Sforza [France] ; L. Laks [Australie] ; R. R. Grunstein [Australie] ; J. Krieger [France] ; C. E. Sullivan [Australie]Source :
- The European respiratory journal [ 0903-1936 ] ; 1998.
Descripteurs français
- Pascal (Inist)
- Wicri :
- topic : Homme.
English descriptors
- KwdEn :
Abstract
Recent results in animals have suggested that repetition of hypoxaemic stimuli may result in a progressive increase in pulmonary arterial pressure (Ppa). The purpose of the present study was to investigate the effects of recurrent obstructive apnoeas on Ppa. We have, therefore, examined the nocturnal trend of Ppa in seven obstructive sleep apnoea syndrome (OSAS) patients and in five snorers. Mean Ppa was measured before, at the start, at the end and after the selected apnoeas. The analysis was performed for each I h period for at least 7 h throughout the night on at least 10 randomly selected apnoeas per hour. In snorers, 100 randomly chosen values were measured during every hour of the night. In the morning after the nocturnal study, the Ppa responses to acute hypoxia and hypercapnia were measured. No Ppa changes throughout the 7 h were found during sleep in snorers (Ppa slope:-0.002±0.10 mmHg.h-1). In OSAS patients a small but significant increase in Ppa throughout the night was noted, affecting the values before (Ppa slope: 0.7+0.16 mm Hg.h-1), at the start of apnoea (Ppa slope: 0.53±0.1 mmHg.h-1) as well as at the end (Ppa slope: 0.44±0.08 mmHg.h-1) and in the postapnoeic period (Ppa slope: 0.55±0.1 mmHg.h-1). When we limited the analysis to nonrapid eye movement (NREM) sleep, a trend in progressive Ppa was also present, irrespective of changes in apnoea duration and apnoea desaturation. The Ppa rise during the night was not affected by diurnal Ppa pulmonary vascular response to hypoxia and hypercapnia or indices of sleep apnoea severity. We conclude that in obstructive sleep apnoea, pulmonary artery pressure progressively increases during the night, reflecting the cumulative effects of apnoeas and nocturnal hypoxaemia.
Affiliations:
- Australie, France
- Alsace (région administrative), Grand Est, Nouvelle-Galles du Sud
- Strasbourg, Sydney
Links toward previous steps (curation, corpus...)
- to stream PascalFrancis, to step Corpus: 006776
- to stream PascalFrancis, to step Curation: 006886
- to stream PascalFrancis, to step Checkpoint: 006224
- to stream Main, to step Merge: 00DB11
- to stream Main, to step Curation: 00CA64
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en" level="a">Time course of pulmonary artery pressure during sleep in sleep apnoea syndrome : role of recurrent apnoeas</title>
<author><name sortKey="Sforza, E" sort="Sforza, E" uniqKey="Sforza E" first="E." last="Sforza">E. Sforza</name>
<affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Sleep Unit, Hopitaux Universitaires de Strasbourg</s1>
<s2>Strasbourg</s2>
<s3>FRA</s3>
<sZ>1 aut.</sZ>
<sZ>4 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName><region type="region">Grand Est</region>
<region type="old region">Alsace (région administrative)</region>
<settlement type="city">Strasbourg</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Laks, L" sort="Laks, L" uniqKey="Laks L" first="L." last="Laks">L. Laks</name>
<affiliation wicri:level="3"><inist:fA14 i1="02"><s1>Sleep Disorder Centre, Royal Prince Alfred Hospital</s1>
<s2>Sydney</s2>
<s3>AUS</s3>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>5 aut.</sZ>
</inist:fA14>
<country>Australie</country>
<placeName><settlement type="city">Sydney</settlement>
<region type="état">Nouvelle-Galles du Sud</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Grunstein, R R" sort="Grunstein, R R" uniqKey="Grunstein R" first="R. R." last="Grunstein">R. R. Grunstein</name>
<affiliation wicri:level="3"><inist:fA14 i1="02"><s1>Sleep Disorder Centre, Royal Prince Alfred Hospital</s1>
<s2>Sydney</s2>
<s3>AUS</s3>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>5 aut.</sZ>
</inist:fA14>
<country>Australie</country>
<placeName><settlement type="city">Sydney</settlement>
<region type="état">Nouvelle-Galles du Sud</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Krieger, J" sort="Krieger, J" uniqKey="Krieger J" first="J." last="Krieger">J. Krieger</name>
<affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Sleep Unit, Hopitaux Universitaires de Strasbourg</s1>
<s2>Strasbourg</s2>
<s3>FRA</s3>
<sZ>1 aut.</sZ>
<sZ>4 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName><region type="region">Grand Est</region>
<region type="old region">Alsace (région administrative)</region>
<settlement type="city">Strasbourg</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Sullivan, C E" sort="Sullivan, C E" uniqKey="Sullivan C" first="C. E." last="Sullivan">C. E. Sullivan</name>
<affiliation wicri:level="3"><inist:fA14 i1="02"><s1>Sleep Disorder Centre, Royal Prince Alfred Hospital</s1>
<s2>Sydney</s2>
<s3>AUS</s3>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>5 aut.</sZ>
</inist:fA14>
<country>Australie</country>
<placeName><settlement type="city">Sydney</settlement>
<region type="état">Nouvelle-Galles du Sud</region>
</placeName>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">INIST</idno>
<idno type="inist">98-0163727</idno>
<date when="1998">1998</date>
<idno type="stanalyst">PASCAL 98-0163727 INIST</idno>
<idno type="RBID">Pascal:98-0163727</idno>
<idno type="wicri:Area/PascalFrancis/Corpus">006776</idno>
<idno type="wicri:Area/PascalFrancis/Curation">006886</idno>
<idno type="wicri:Area/PascalFrancis/Checkpoint">006224</idno>
<idno type="wicri:explorRef" wicri:stream="PascalFrancis" wicri:step="Checkpoint">006224</idno>
<idno type="wicri:doubleKey">0903-1936:1998:Sforza E:time:course:of</idno>
<idno type="wicri:Area/Main/Merge">00DB11</idno>
<idno type="wicri:Area/Main/Curation">00CA64</idno>
<idno type="wicri:Area/Main/Exploration">00CA64</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">Time course of pulmonary artery pressure during sleep in sleep apnoea syndrome : role of recurrent apnoeas</title>
<author><name sortKey="Sforza, E" sort="Sforza, E" uniqKey="Sforza E" first="E." last="Sforza">E. Sforza</name>
<affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Sleep Unit, Hopitaux Universitaires de Strasbourg</s1>
<s2>Strasbourg</s2>
<s3>FRA</s3>
<sZ>1 aut.</sZ>
<sZ>4 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName><region type="region">Grand Est</region>
<region type="old region">Alsace (région administrative)</region>
<settlement type="city">Strasbourg</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Laks, L" sort="Laks, L" uniqKey="Laks L" first="L." last="Laks">L. Laks</name>
<affiliation wicri:level="3"><inist:fA14 i1="02"><s1>Sleep Disorder Centre, Royal Prince Alfred Hospital</s1>
<s2>Sydney</s2>
<s3>AUS</s3>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>5 aut.</sZ>
</inist:fA14>
<country>Australie</country>
<placeName><settlement type="city">Sydney</settlement>
<region type="état">Nouvelle-Galles du Sud</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Grunstein, R R" sort="Grunstein, R R" uniqKey="Grunstein R" first="R. R." last="Grunstein">R. R. Grunstein</name>
<affiliation wicri:level="3"><inist:fA14 i1="02"><s1>Sleep Disorder Centre, Royal Prince Alfred Hospital</s1>
<s2>Sydney</s2>
<s3>AUS</s3>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>5 aut.</sZ>
</inist:fA14>
<country>Australie</country>
<placeName><settlement type="city">Sydney</settlement>
<region type="état">Nouvelle-Galles du Sud</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Krieger, J" sort="Krieger, J" uniqKey="Krieger J" first="J." last="Krieger">J. Krieger</name>
<affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Sleep Unit, Hopitaux Universitaires de Strasbourg</s1>
<s2>Strasbourg</s2>
<s3>FRA</s3>
<sZ>1 aut.</sZ>
<sZ>4 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName><region type="region">Grand Est</region>
<region type="old region">Alsace (région administrative)</region>
<settlement type="city">Strasbourg</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Sullivan, C E" sort="Sullivan, C E" uniqKey="Sullivan C" first="C. E." last="Sullivan">C. E. Sullivan</name>
<affiliation wicri:level="3"><inist:fA14 i1="02"><s1>Sleep Disorder Centre, Royal Prince Alfred Hospital</s1>
<s2>Sydney</s2>
<s3>AUS</s3>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>5 aut.</sZ>
</inist:fA14>
<country>Australie</country>
<placeName><settlement type="city">Sydney</settlement>
<region type="état">Nouvelle-Galles du Sud</region>
</placeName>
</affiliation>
</author>
</analytic>
<series><title level="j" type="main">The European respiratory journal</title>
<title level="j" type="abbreviated">Eur. respir. j.</title>
<idno type="ISSN">0903-1936</idno>
<imprint><date when="1998">1998</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
<seriesStmt><title level="j" type="main">The European respiratory journal</title>
<title level="j" type="abbreviated">Eur. respir. j.</title>
<idno type="ISSN">0903-1936</idno>
</seriesStmt>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Apnea</term>
<term>Arterial pressure</term>
<term>Exploration</term>
<term>Human</term>
<term>Hypoxemia</term>
<term>Monitoring</term>
<term>Pulmonary artery</term>
<term>Sleep</term>
</keywords>
<keywords scheme="Pascal" xml:lang="fr"><term>Apnée</term>
<term>Sommeil</term>
<term>Hypoxémie</term>
<term>Monitorage</term>
<term>Pression artérielle</term>
<term>Artère pulmonaire</term>
<term>Exploration</term>
<term>Homme</term>
</keywords>
<keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Homme</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">Recent results in animals have suggested that repetition of hypoxaemic stimuli may result in a progressive increase in pulmonary arterial pressure (Ppa). The purpose of the present study was to investigate the effects of recurrent obstructive apnoeas on Ppa. We have, therefore, examined the nocturnal trend of Ppa in seven obstructive sleep apnoea syndrome (OSAS) patients and in five snorers. Mean Ppa was measured before, at the start, at the end and after the selected apnoeas. The analysis was performed for each I h period for at least 7 h throughout the night on at least 10 randomly selected apnoeas per hour. In snorers, 100 randomly chosen values were measured during every hour of the night. In the morning after the nocturnal study, the Ppa responses to acute hypoxia and hypercapnia were measured. No Ppa changes throughout the 7 h were found during sleep in snorers (Ppa slope:-0.002±0.10 mmHg.h<sup>-1</sup>
). In OSAS patients a small but significant increase in Ppa throughout the night was noted, affecting the values before (Ppa slope: 0.7+0.16 mm Hg.h<sup>-1</sup>
), at the start of apnoea (Ppa slope: 0.53±0.1 mmHg.h<sup>-1</sup>
) as well as at the end (Ppa slope: 0.44±0.08 mmHg.h<sup>-1</sup>
) and in the postapnoeic period (Ppa slope: 0.55±0.1 mmHg.h<sup>-1</sup>
). When we limited the analysis to nonrapid eye movement (NREM) sleep, a trend in progressive Ppa was also present, irrespective of changes in apnoea duration and apnoea desaturation. The Ppa rise during the night was not affected by diurnal Ppa pulmonary vascular response to hypoxia and hypercapnia or indices of sleep apnoea severity. We conclude that in obstructive sleep apnoea, pulmonary artery pressure progressively increases during the night, reflecting the cumulative effects of apnoeas and nocturnal hypoxaemia.</div>
</front>
</TEI>
<affiliations><list><country><li>Australie</li>
<li>France</li>
</country>
<region><li>Alsace (région administrative)</li>
<li>Grand Est</li>
<li>Nouvelle-Galles du Sud</li>
</region>
<settlement><li>Strasbourg</li>
<li>Sydney</li>
</settlement>
</list>
<tree><country name="France"><region name="Grand Est"><name sortKey="Sforza, E" sort="Sforza, E" uniqKey="Sforza E" first="E." last="Sforza">E. Sforza</name>
</region>
<name sortKey="Krieger, J" sort="Krieger, J" uniqKey="Krieger J" first="J." last="Krieger">J. Krieger</name>
</country>
<country name="Australie"><region name="Nouvelle-Galles du Sud"><name sortKey="Laks, L" sort="Laks, L" uniqKey="Laks L" first="L." last="Laks">L. Laks</name>
</region>
<name sortKey="Grunstein, R R" sort="Grunstein, R R" uniqKey="Grunstein R" first="R. R." last="Grunstein">R. R. Grunstein</name>
<name sortKey="Sullivan, C E" sort="Sullivan, C E" uniqKey="Sullivan C" first="C. E." last="Sullivan">C. E. Sullivan</name>
</country>
</tree>
</affiliations>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Asie/explor/AustralieFrV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 00CA64 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 00CA64 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Wicri/Asie |area= AustralieFrV1 |flux= Main |étape= Exploration |type= RBID |clé= Pascal:98-0163727 |texte= Time course of pulmonary artery pressure during sleep in sleep apnoea syndrome : role of recurrent apnoeas }}
This area was generated with Dilib version V0.6.33. |